#6
The extreme allergic reaction, anaphylactic shock, has been studied extensively in guinea pigs, which display this reaction more readily and strongly than most other species. Guinea pigs' airways are sensitive to allergens, so it has been widely used in asthma studies. The inhaled medications that are the mainstays of asthma treatment were developed using guinea pigs as were orally-active drugs for asthma such as montelukast. Guinea pigs continue to be useful for the development of improved treatments for asthma, and they are also used in the testing of vaccines against anthrax, currently an important area of biodefence research, and new medicines to treat drug-resistant tuberculosis.
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